Hydroxypropyl Methyl Cellulose Phthalate
Hosea Chem® has been supplying Hydroxypropyl Methyl Cellulose Phthalate (HPMCP) with high quality and competitive price for many years, covering most of the European, American, etc. Send Inquiry
Product Description
Hydroxypropyl Methyl Cellulose Phthalate
Specification of Product
Product Name : Hydroxypropyl Methyl Cellulose Phthalate (HPMCP)
Cas No.: 9050-31-1
Molecular formula: (C36H44O19)N
Hydroxypropyl Methyl Cellulose Phthalate Physical Data
HO55 HO555 HO-50
Viscosity，mPa.s 32-48 136-204 44-66
Free Phthalic Acid, % ≤ 1.0 ≤ 1.0
Phthaloyl Groups, % 27.0-35.0 21.0-27.0
Hydroxypropyl Groups, % 5.0-9.0 6.0-10.0
Methoxy Groups, % 18.0-22.0 20.0-24.0
Loss on Drying, % ≤ 5.0
Residue on Ignition, % ≤ 0.2
Chloride, % ≤ 0.07
Arsenic, % ≤ 2
Heavy Metals, % ≤ 0.001
Hydroxypropyl Methyl Cellulose Phthalate Properties
This product is an odorless and tasteless white powder or granules; the bulk density is 0.26-0.79g/cm3; it is soluble in organic solvents such as acetone, acetone/water (95/5), acetone/ethanol (1/1), dichloromethane/ethanol (1/1), ethanol/water (8/2), etc. It is insoluble in water and acidic buffer.
Packaging, transportation, and storage
Package：25Kgs/Bag or Drum.
This product should be stored in a dry, light-proof indoor warehouse to prevent moisture.
During the storage, transportation and loading and unloading of this product, avoid rain; avoid direct sunlight; ensure that it is dry and the packaging bag is not damaged or contaminated by other items; do not mix or store with toxic or harmful items; do not store at high temperatures.
Hydroxypropyl Methyl Cellulose Phthalate Applications
This product is an excellent enteric coating material with a defined viscosity and excellent gastric acid resistance. It is insoluble at pH 5.0-5.5. The dosage for tablets is 5%-10% by weight, with a concentration of 6%-8%. It is primarily used as a tablet and granule frame material, adhesive, implant, and flavor enhancer. It is also widely used in aquaculture, industry, and biotechnology.
Coating Solution Preparation: The HPMCP concentration is generally 3-6% of the total solution weight. Organic solvents used include chloromethane/ethanol (1/1), acetone/ethanol (1/1), and ethanol/water (8/2).
Dissolution Method: Add a predetermined amount of solvent to a container. While stirring, slowly add the HPMCP, stirring evenly, and allow to dissolve for 20-50 minutes. HPMCP dosage is generally 6-10% of the tablet core weight.